Effect of Amphetamine on Neurotransmitter Release and ReuptakeAuthor Paul Kenyon
catecholamines (especially dopamine) from synaptic vesicles in nerve
terminals. Note that amphetamine
causes a massive release of DA from synaptic vesicles within the
presynaptic nerve ending which causes the postsynaptic neuron to fire.
1. Bridging the information gap between neurones
Neurotransmitters are responsible for transmitting information across the synaptic gap between neurones.
Neurotransmitters are stored in synaptic vesicles. When amphetamine is administered:
Neurotransmitters in the synaptic cleft :
2. 'Mopping up' after information transmission
transmitters have been released into the synaptic cleft.